Laboratory of Developmental Programming
and Immuno-Physiology

The Hong lab is a part of the Department of Systems Biology at the Yonsei University in Seoul. Our overarching goal is to understand how perinatal environment results in long-term changes in later-life immunity and physiology. Our work particularly emphasizes the role of internal signaling molecules such as hormones and metabolites in developmental programming. In spite of accumulated cases of long-term immune and metabolic alteration by perinatal environmental factors, the biological rationale behind this phenomenon is still elusive. The knowledge acquired by our study should have great impact in human health and disease with showing the origin of disease susceptibility.